Top ten drugs that cause kidney damage

Night_Hawk

Siasat.pk - Blogger
TOP TEN DRUGS THAT CAUSE KIDNEY DAMAGE


November 24, 2016
The list of individual drugs that cause kidney damage is so long that its hard to decide on the top ten. So Ive chosen to list them by type of drug: antibiotic, analgesic, etc.


Top ten drugs that cause kidney damage:
1. Antibiotics, including ciprofloxacin, methicillin, vancomycin, sulfonamides.

2. Analgesics, including acetominophen and non-steroidal anti-inflammatory drugs (NSAID): aspirin, ibuprofen, naproxen, and others available only by prescription.



3. COX-2 inhibitors, including celecoxib (brand name Celebrex). Two drugs in this class have been withdrawn from the market because of cardiovascular toxicity: rofecoxib (brand name Vioxx), and valdecoxib (brand name Bextra). These drugs are a special class of NSAID that were developed to be safer for the stomach, but have the same risk as other NSAIDs for kidney damage.


4. Heartburn drugs of the proton pump inhibitor class, including omeprazole (brand name Prilosec), lansoprazole (brand name Prevacid), pantoprazole (brand name Protonix), rabeprazol (brand names Rabecid, Aciphex), esomeprazole (brand names Nexium, Esotrex). See Ref. 4.

5. Antiviral drugs, including acyclovir (brand name Zovirax) used to treat herpes infection, and indinavir and tenofovir, both used to treat HIV.



6. High blood pressure drugs, including captopril (brand name Capoten).



7. Rheumatoid arthritis drugs, including infliximab (brand name Remicade); chloroquine and hydroxychloroquine, which are used to treat malaria and systemic lupus erythematosus as well as rheumatoid arthritis.


8. Lithium, used to treat bipolar disorder.



9. Anticonvulsants, including phenytoin (brand name Dilantin) and trimethadione (brand name Tridione), used to treat seizures and other conditions.



10. Chemotherapy drugs, including interferons, pamidronate, cisplatin, carboplatin, cyclosporine, tacrolimus, quinine, mitomycin C, bevacizumab; and anti-thyroid drugs, including propylthiouracil, used to treat overactive thyroid.

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Raaz

(50k+ posts) بابائے فورم
اس کا سورس کیا ہے ؟؟؟


دوا کا ٹھیک استمعال ضروری ہے

اور یہ مطلب نہی کہ آپ دوا نہ لیں اور بلڈ پریشر بڑھتا رہے حتاکہ آپ پر سٹروک ہو جاۓ
یا دوسرے آرگن خراب ہو جائیں

غلط تھریڈ نہ لگایا کریں ، پلیز
آپ ڈاکٹر تو نہی ہیں ، اس لئے ڈاکٹر بننے کی کوشش نہ کریں

ماینڈ نہ کیجئے
 

Night_Hawk

Siasat.pk - Blogger
اس کا سورس کیا ہے ؟؟؟


دوا کا ٹھیک استمعال ضروری ہے

اور یہ مطلب نہی کہ آپ دوا نہ لیں اور بلڈ پریشر بڑھتا رہے حتاکہ آپ پر سٹروک ہو جاۓ
یا دوسرے آرگن خراب ہو جائیں

غلط تھریڈ نہ لگایا کریں ، پلیز
آپ ڈاکٹر تو نہی ہیں ، اس لئے ڈاکٹر بننے کی کوشش نہ کریں

ماینڈ نہ کیجئے

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شکریہ راز صاحب۔ آپ نے بہت اچھی بات لکھی ہے۔ میں آپ کی نصیحت کا بہت مشکور ہوں۔ آیندہ احتیاط کروںگا۔
دوائیوں کے نقصانات تو ہوتے ہیں۔ اس آرٹیکل میں یہ کہیں نہیں لکھا کہ آپ دوا نہ کھائیں اور نہ ہی میں نے اپنی طرف سے کویئ ایسی بات لکھی ہے۔ یہ دوا کھانے والے کے لئیے بہت ضروری ہے کہ دوا کے مضر اثرات کا بھی علم ہو۔



 

Raaz

(50k+ posts) بابائے فورم
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شکریہ راز صاحب۔ آپ نے بہت اچھی بات لکھی ہے۔ میں آپ کی نصیحت کا بہت مشکور ہوں۔ آیندہ احتیاط کروںگا۔
دوائیوں کے نقصانات تو ہوتے ہیں۔ اس آرٹیکل میں یہ کہیں نہیں لکھا کہ آپ دوا نہ کھائیں اور نہ ہی میں نے اپنی طرف سے کویئ ایسی بات لکھی ہے۔ یہ دوا کھانے والے کے لئیے بہت ضروری ہے کہ دوا کے مضر اثرات کا بھی علم ہو۔




نہی یہ بات نہی ہے
بات یہ ہے دوا کی کونٹرا انڈیکیشن ہر وقت نہی ہوتی ، اور کسی کسی آدمی پر ہوتی ہے

جیسے آپریشن میں نناوے فیصد ٹھیک ہوجاتے ہیں لیکن ایک فیصد کیس خراب بھی ہو جاتا ہے

اب اس ایک فیصد کو لے کر آپ آرٹیکل لکھیں اور لوگوں کو ڈرائیں کہ آپریشن میں آپ مر سکتے ہیں تو یہ ٹھیک نہی ہوگا

کہ اگر بلڈ پریشر زیادہ ہو تو اس کی دوا لینی چاہے ، نہ کہ کسی اس کے برے اثرات سے لوگوں کو ڈرایا جاۓ

آپ اچھے آرٹیکل پوسٹ کریں جس میں لوگوں کو ٹھیک طریقے سے دو ا لینے کی تربیت ہو

آپ خود بھی دوا لیتے ہوں گے

لیکن پاکستان کے ایسے ایسے لوگ موجود ہیں جو بلڈ پریشر تک کی دوا نہی لیتے ، اور کسی بڑی مشکل میں پڑتے ہیں ، کیوں کہ یہ بیماریوں کی جڑ ہے
 

Night_Hawk

Siasat.pk - Blogger
[h=1]Kidney Disease: Medicines to Avoid - Topic Overview[/h]
[h=3]Kidney Disease: Medicines to Avoid
[/h] Many medicines may impair kidney function and cause kidney damage. And if your kidneys aren't working well, medicines can build up in your body. If you have chronic kidney disease, your doctor may advise you to continue to take a medicine but may change how much you take. Or you may change to a different medicine. Don't stop taking any prescription medicines without talking to your doctor first.
It is important to talk to your doctor or pharmacist about all prescription, over-the-counter, and herbal products that you take. Be safe with medicines. Read and follow all instructions on the label.
Some examples of common medicines that may need to be avoided, adjusted, or changed:

  • Pain medicines, including:
    • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen. NSAIDs can reduce the flow of blood to your kidneys. NSAIDs are also found in medicines for fever, colds and coughs, and sleep problems.
    • Acetaminophen and aspirin may be harmful if overused. They are usually safe in small amounts.
  • Herbal supplements, which can contain minerals like potassium that are harmful for people who have kidney disease. Many herbs can interact with prescription medicines. Always check with your doctor or pharmacist before you take herbal products.
  • Statin medicines, such as atorvastatin, lovastatin, and simvastatin, for high cholesterol.
  • Diabetes medicines, including insulin and metformin.
  • Heartburn and upset-stomach medicines, such as Milk of Magnesia and Alka-Seltzer. These medicines can affect your electrolytes.
  • Antimicrobial medicines, including some antibiotics, anti-fungal, and antiviral medicines.

http://www.webmd.com/a-to-z-guides/tc/kidney-disease-medicines-to-avoid-topic-overview





 

Night_Hawk

Siasat.pk - Blogger
@Raaz Sahib the above article in post #5 and the article in the first post ,(post #1) I never claimed that I wrote hose articles.
The purpose of these articles to make an awareness in peoples mind to be cautious and ask questions from your Doctors.
Be an educated patient.
None of the article suggested to stop taking your medications.
There are always alternate medicines to treat the same medical condition.
Frequent blood tests are usually recommended to see the side effects of the medicine on kidneys .



 

Night_Hawk

Siasat.pk - Blogger







[h=1]Medical Tests of Kidney Function[/h] Healthy kidneys remove wastes and excess fluid from the blood. Blood tests show whether the kidneys are failing to remove wastes. Urine tests can show how quickly body wastes are being removed and whether the kidneys are also leaking abnormal amounts of protein.

[h=2]Blood Tests[/h] Serum Creatinine
Creatinine (kree-AT-uh-nin) is a waste product that comes from meat protein in the diet and also comes from the normal wear and tear on muscles of the body. Creatinine levels in the blood can vary, and each laboratory has its own normal range. In many labs the normal range is 0.6 to 1.2 mg/dl. Higher levels may be a sign that the kidneys are not working properly. As kidney disease progresses, the level of creatinine in the blood increases.
Blood Urea Nitrogen (BUN)
Urea nitrogen (yoo-REE-uh NY-truh-jen) also is produced from the breakdown of food protein. A normal BUN level is between 7 and 20 mg/dl. As kidney function decreases, the BUN level increases.
Urine Tests
Some urine tests require only a few ounces of urine. But some tests require collection of all urine produced for a full 24 hours. A 24-hour urine test shows how much urine your kidneys produce in 1 day. The test also can give an accurate measurement of how much protein leaks from the kidney into the urine in 1 day.
Creatinine Clearance
A creatinine clearance test compares the creatinine in a 24-hour sample of urine to the creatinine level in the blood, to show how many milliliters of blood the kidneys are filtering out each minute (ml/min).
[h=2]For More Information[/h] American Kidney Fund

6110 Executive Boulevard

Rockville, MD 20852

(800) 638-8299

National Kidney Foundation

30 East 33rd Street

New York, NY 10016

(800) 622-9010


[h=2]Additional Information on Medical Tests of Kidney Function[/h] The National Kidney and Urologic Diseases Information Clearinghouse collects resource information on kidney and urologic diseases for the Combined Health Information Database (CHID). CHID is a database produced by health-related agencies of the Federal Government. This database provides titles, abstracts, and availability information for health information and health education resources.
To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of CHID. Or, if you wish to perform your own search of the database, you may access the CHID Online web site ( http://chid.nih.gov ) and search CHID yourself.



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Night_Hawk

Siasat.pk - Blogger
[h=1]Kidney Function Tests
[/h]
Written by Debra Stang
Medically Reviewed by Steven Kim, MD on October 15, 2015

[h=2] Overview of Kidney Function Tests[/h] You have two kidneys on either side of your spine that are each approximately the size of a human fist. Theyre located posterior to your abdomen and below your rib cage.
Your kidneys play several vital roles in maintaining your health. One of their most important jobs is to filter waste materials from the blood and expel them from the body as urine. The kidneys also help control the levels of water and various essential minerals in the body. In addition, theyre critical to the production of:

  • vitamin D
  • red blood cells
  • hormones that regulate blood pressure
If your doctor thinks your kidneys may not be working properly, you may need kidney function tests. These are simple blood and urine tests that can identify problems with your kidneys.
You may also need kidney function testing done if you have other conditions that can harm the kidneys, such as diabetes or high blood pressure. They can help doctors monitor these conditions.

[h=2] Symptoms of Kidney Problems[/h] Symptoms that may indicate a problem with your kidneys include:

  • high blood pressure
  • blood in the urine
  • frequent urges to urinate
  • difficulty beginning urination
  • painful urination
  • swelling of the hands and feet due to a buildup of fluids in the body
A single symptom may not mean something serious. However, when occurring simultaneously, these symptoms suggest that your kidneys arent working properly. Kidney function tests can help determine the reason.

[h=2] Types of Kidney Function Tests[/h] To test your kidney function, your doctor will order a set of tests that can estimate your glomerular filtration rate (GFR). Your GFR tells your doctor how quickly your kidneys are clearing waste from your body.
[h=3]Urinalysis[/h] A urinalysis screens for the presence of protein and blood in the urine. There are many possible reasons for protein in your urine, not all of which are related to disease. Infection increases urine protein, but so does a heavy physical workout. Your doctor may want to repeat this test after a few weeks to see if the results are similar.
Your doctor may also ask you to provide a 24-hour urine collection sample. This can help doctors see how fast a waste product called creatinine is clearing from your body. Creatinine is a breakdown product of muscle tissue.
[h=3]Serum Creatinine Test[/h] This blood test examines whether creatinine is building up in your blood. The kidneys usually completely filter creatinine from the blood. A high level of creatinine suggests a kidney problem.
According to the National Kidney Foundation (NKF), a creatinine level higher than 1.2 for women and 1.4 for men is a sign of a kidney problem.
[h=3]Blood Urea Nitrogen (BUN)[/h] The blood urea nitrogen (BUN) test also checks for waste products in your blood. BUN tests measure the amount of nitrogen in the blood. Urea nitrogen is a breakdown product of protein. However, not all elevated BUN tests are due to kidney damage. Common medications, including large doses of aspirin and some types of antibiotics, can also increase your BUN. Its important to tell your doctor about any medications or supplements that you take regularly. You may need to stop certain drugs for a few days before the test.
A normal BUN level is between 7 and 20. A higher value could suggest several different health problems.
[h=3]Estimated Glomerular Filtration Rate (GFR)[/h] This test estimates how well your kidneys are filtering waste. The test determines the rate by looking at factors, such as:

  • test results, specifically creatinine levels
  • age
  • gender
  • race
  • height
  • weight
Any result lower than 60 may be a warning sign of kidney disease.

[h=2] How the Tests Are Obtained[/h] Kidney function tests usually require a 24-hour urine sample and a blood test.
[h=3]24-Hour Urine Sample[/h] A 24-hour urine sample is a creatinine clearance test. It gives your doctor an idea of how much creatinine your body expels over a single day.
On the day that you start the test, urinate into the toilet as you normally would when you wake up.
For the rest of the day and night, urinate into a special container provided by your doctor. Keep the container capped and refrigerated during the collection process. Make sure to label the container clearly and to tell other family members why its in the refrigerator.
On the morning of the second day, urinate into the container when you get up. This completes the 24-hour collection process.
Cap and label the container, and follow your doctors instructions about where to drop it off. You may need to return it either to your doctors office or a laboratory.
[h=3]Blood Samples[/h] BUN and serum creatinine tests require blood samples taken in a lab or doctors office.
The technician drawing the blood will tie an elastic band around your upper arm. This makes the veins stand out. The technician will clean the area over the vein. They will then slip a hollow needle through your skin and into the vein. The blood will flow back into a test tube that will be sent for analysis.
You may feel a sharp pinch or prick when the needle enters your arm. The technician will place gauze and a bandage over the puncture site after the test. The area around the puncture may develop a bruise over the next few days. However, you shouldnt feel severe or long-term pain.

[h=2] Treatment of Early Kidney Disease[/h] Your doctor will focus on treating the underlying condition if the tests show early kidney disease. Your doctor will prescribe medications to control the blood pressure if the tests indicate hypertension. Theyll also suggest lifestyle and dietary modifications.
If you have diabetes, your doctor may want you to see an endocrinologist. This type of doctor specializes in metabolic diseases and can help ensure that you have the best blood glucose control possible.
If there are other causes of your abnormal kidney function tests, such as kidney stones and excessive use of pain killers, your doctor will take appropriate measures to manage those disorders.
Abnormal test results mean youll probably need regular kidney function tests in the months ahead. These will help your doctor keep an eye on your condition.


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