Kidney disease 'biggest threat' for diabetics

Night_Hawk

Siasat.pk - Blogger
24 January 2013 Last updated at 20:50 ET

[h=1]Kidney disease 'biggest threat' for diabetics[/h]
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Kidney disease can be a complication arising from diabetes
Continue reading the main story

Keeping your kidneys healthy could be one of the best ways to extend your life if you have Type 2 diabetes, researchers have suggested.
The University of Washington study found that having kidney disease meant a much higher risk of early death.
UK experts say that the NHS is still not putting enough effort into detecting and controlling kidney problems caused by diabetes.
Figures from 2012 suggest only seven in 10 patients get vital annual checks.
Approximately 5% of people in the UK have been diagnosed with diabetes, and careful management of their condition through a combination of medication and lifestyle changes can mean it has relatively little impact on their lives.
However, if the disease has been present for some time prior to diagnosis, or is poorly managed afterwards, the risk of life-changing complications rises.
These include eye and lower limb problems, and kidney problems.

[h=2]Start QuoteThere really is no excuse for this - there is clear guidance saying that kidney function should be tested.[/h] Cathy Moulton Diabetes UK

The research, in the Journal of the American Society of Nephrology, looked at mortality rates over a 10-year period in more than 15,000 adults, with and without diabetes.
Kidney disease was present in 9.4% of the people without diabetes, and 42.3% of those with diabetes.
They found that 7.7% of those without diabetes or kidney disease died over the course of the decade-long study.
This rose to 11.5% for people with diabetes but no kidney disease, but soared to 31.1% for people with diabetes and kidney disease.
'No excuse' Lead researcher Dr Maryam Afkarian said: "People with type-two diabetes have many other risk factors for cardiovascular disease and mortality, so we expected that kidney disease would predict a part, but not a majority, of higher mortality."
Singling this group of patients out for intensive treatment, or working harder to prevent kidney disease from taking hold, could be a powerful way of reducing deaths among people with diabetes, she added.
Cathy Moulton, a clinical adviser at Diabetes UK, said that if detected early, diabetic kidney disease could be controlled using blood pressure medication.
However, the charity's 2012 report found that as many as three in 10 patients were missing out the simple blood or urine tests that would reveal their kidney problems.
She said: "There really is no excuse for this - there is clear guidance saying that kidney function should be tested.
"Very often the doctor will be taking blood for other purposes, such as checking cholesterol levels, so it is the easiest thing in the world to do."
Kidney failure would cost the NHS thousands more in expensive dialysis treatments, she added.
Diabetes UK has compiled a list of 15 "healthcare essentials" that it says every patient with the disease should read and ensure they are receiving from the NHS.

http://www.bbc.co.uk/news/health-21184232
 

Night_Hawk

Siasat.pk - Blogger
15 healthcare essentials
Having the right care is essential for the wellbeing of all people with diabetes. There is a
minimum level of healthcare that every person with diabetes deserves and should expect.
Here are the 15 essential checks and services you should receive. If you arent
getting all the care you need, take this checklist to your diabetes healthcare team and
discuss it with them.

1 Get your blood glucose levels measured at least once a year. An HbA1c
blood test will measure your overall blood glucose control and help you and your
diabetes healthcare team set your own target.

2 Have your blood pressure measured and recorded at least once a year,
and set a personal target that is right for you.

3 Have your blood fats (cholesterol) measured every year. Like blood
glucose levels and blood pressure, you should have your own target that is
realistic and achievable.

4 Have your eyes screened for signs of retinopathy every year. Using a
specialised digital camera, a photo of each eye will be taken and examined by
a specialist who will look for any changes to your retina (the seeing part at the
back of your eye).

5 Have your feet checked the skin, circulation and nerve supply of your
feet should be examined annually. You should be told if you have any risk of
foot problems, how serious they are and if you will be referred to a specialist
podiatrist or specialist foot clinic.
6 Have your kidney function monitored annually. You should have two
tests for your kidneys: urine test for protein (a sign of possible kidney problems)
and a blood test to measure kidney function.

7 Have your weight checked and have your waist measured to see if you
need to lose weight.

8 Get support if you are a smoker including advice and support on how to
quit. Having diabetes already puts people at increased risk of heart disease
and stroke, and smoking further increases this risk.

The care you should receive
9 Receive care planning to meet your individual needs you live with
diabetes every day so you should have a say in every aspect of your care. Your
yearly care plan should be agreed as a result of a discussion between you and
your diabetes healthcare team, where you talk about your individual needs and
set targets.*

10 Attend an education course to help you understand and manage your
diabetes. You should be offered and have the opportunity to attend courses in
your local area.

11 Receive pediatric care if you are a child or young person. You
should receive care from specialist diabetes pediatric healthcare
professionals. When the time comes to leave pediatric care, you should know
exactly what to expect so you have a smooth change over to adult health
services.

12 Receive high quality care if admitted to hospital. If you have to stay
in hospital, you should still continue to receive high-quality diabetes care from
specialist diabetes healthcare professionals, regardless of whether you have
been admitted due to your diabetes or not.

13 Get information and specialist care if you are planning to have a
baby as your diabetes control has to be a lot tighter and monitored very
closely. You should expect care and support from specialist healthcare
professionals at every stage from preconception to post-natal care.

14 See specialist diabetes healthcare professionals to help you manage
your diabetes. Diabetes affects different parts of the body and you should have
the opportunity to see specialist professionals such as an ophthalmologist,
podiatrist or dietitian.

15 Get emotional and psychological support. Being diagnosed with
diabetes and living with a long term condition can be difficult. You should be
able to talk about your issues and concerns with specialist healthcare
professionals.
Checks and services for children. Children should receive more frequent HbA1c
measurements and regular weight, height and general health checks from their
healthcare team. Formal screening for complications generally begin at age 12.
 

Night_Hawk

Siasat.pk - Blogger
[h=1]Diet 'can reverse kidney failure' in mice with diabetes[/h]
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The ketogenic diet is 87% fat


A controlled diet high in fat and low in carbohydrate can repair kidney damage in diabetic mice, according to US scientists.

The study, published in journal PLoS ONE, showed a "ketogenic diet" could reverse damage caused to tubes in the kidneys by too much sugar in the blood.
In the UK around a third of the 2.8m people with either type 1 or 2 diabetes go on to develop kidney damage.
Diabetes UK said it was "questionable" whether humans could sustain the diet.
Damage reversed The researchers at the Mount Sinai School of Medicine in New York used mice with both type 1 and type 2 diabetes.
Once kidney damage had developed, half the mice were put onto the ketogenic diet for eight weeks.

[h=2]“Start QuoteIt is also questionable whether the diet used in this model would be sustainable for humans, even in the short term.”[/h] Dr Iain Frame Diabetes UK

The highly controlled diet, which is 87% fat, mimics the effect of starvation and should not be used without medical advice.
After eight weeks the researchers noted that kidney damage was reversed.
Professor Charles Mobbs, who led the research at Mount Sinai School of Medicine, said: "Our study is the first to show that a dietary intervention alone is enough to reverse this serious complication of diabetes.
"I certainly think it has promise, but I can't recommend it until we have done clinical trials."
The researchers also need to figure out the exact process that leads to repair.
Dr Iain Frame, director of research at Diabetes UK, said: "This research was carried out in mice so it is difficult to see how these results would translate into any real benefits for people with diabetes at this stage.
"It is too simple to say that kidney failure could be prevented by diet alone and it is also questionable whether the diet used in this model would be sustainable for humans, even in the short term."
Helen Nickerson, from the Juvenile Diabetes Research Foundation, which part funded the research, said: "Dr Mobbs' novel observation could lead to new molecular insights in diabetic kidney disease."
http://www.bbc.co.uk/news/health-13134292
 

Night_Hawk

Siasat.pk - Blogger
Thursday, 20 September, 2001, 11:41 GMT 12:41 UK Drug delays diabetic kidney failure

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Dialysis is used to treat patients with kidney failure


One of the most serious complications of diabetes could be delayed for up to two years, say experts. The finding is published in the New England Journal of Medicine after three studies carried out by pharmaceutical companies into preventing kidney failure.
However, although the drug appears to improve patients' quality of life, none of the treatments could prevent kidney damage altogether, or keep patients alive for longer.
Over 80% of diabetics in the UK have Type II disease, otherwise known as adult onset diabetes.

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On average, a reprieve from end-stage renal disease of about two years seems to have been gained
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[TD="bgcolor: CCCC99"] Dr Thomas Hostetter, National Institute of Diabetes and Digestive and Kidney Diseases
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Up to 30% will develop kidney disease, particularly those who suffer from high blood pressure. Kidney disease from diabetes is the most common cause of chronic renal failure leading to dialysis or transplantation.
In an editorial in the New England Journal of Medicine, Dr Thomas Hostetter, of the US National Institute of Diabetes and Digestive and Kidney Diseases said: "On average, a reprieve from end-stage renal disease of about two years seems to have been gained."
Trials
In one study, 1,513 patients in 29 countries including the UK, who had Type II diabetes and early indicators of kidney disease, and who were also on high blood pressure treatment were followed for over three years.
They were given the drug lorsarten or a placebo.
The research was sponsored by Merck Sharp and Dohme, who make the drugs under the brand names Cozaar, already approved to treat hypertension, and Hyzaar.
The study showed the risk of renal failure rates was cut by 28% if people were on the drug, but it had no effect on death rates.
In a second study 1,715 patients were treated with irbesartan, sold as Avapro, or a placebo.
The researchers, led by Dr Edmund Lewis of the Rush-Presbyterian - ST Luke's Medical Centre in Chicago, found the risk of further kidney damage, kidney failure or death dropped by 20% in those taking the drug.
French drug company Sanofi-Synthelabo and American company Bristol-Myers Squibb funded the research.
'Excellent news'
They also funded a study of 590 people with Type II diabetes, high blood pressure and early signs of kidney failure, where patients again took irbesartan or a placebo.
Fifteen per cent of those who had taken the placebo showed signs of kidney damage over the two year study, compared to 5% who took 300 milligrams of irbesartan each day, and 10% who took 150 milligrams.
Suzanne Lucas, director of care at Diabetes UK, said: "This is excellent news for a group of patients whose diabetes puts them at risk of serious complications such as heart disease, stroke, kidney failure, amputation and blindness."
A spokesperson for the National Kidney Research Fund said the studies were "tremendously important in providing hope that the need for dialysis or a kidney transplant can be delayed or prevented in patients with diabetes."
 

Night_Hawk

Siasat.pk - Blogger
[h=2]Tools & Resources[/h]






[h=2]The Hemoglobin A1c (HbA1c) Test for Diabetes[/h]


[h=3]Importance of Hemoglobin A1c Test[/h] The hemoglobin A1c test -- also called HbA1c, glycated hemoglobin test, or glycohemoglobin -- is an important blood test used to determine how well your diabetes is being controlled. Hemoglobin A1c provides an average of your blood sugar control over a six to 12 week period and is used in conjunction with home blood sugar monitoring to make adjustments in your diabetes medicines.
Hemoglobin is a substance within red blood cells that carries oxygen throughout your body. When your diabetes is not controlled (meaning that your blood sugar is too high), sugar builds up in your blood and combines with your hemoglobin, becoming "glycated." Therefore, the average amount of sugar in your blood can be determined by measuring a hemoglobin A1c level. If your glucose levels have been high over recent weeks, your hemoglobin A1c test will be higher. The amount of hemoglobin A1c will reflect the last several weeks of blood sugar levels, typically encompassing a period of 120 days.

[h=4]Recommended Related to Diabetes[/h]

Diabetes,Insulin Dependent
Important It is possible that the main title of the report Diabetes, Insulin Dependent is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.


Read the Diabetes,Insulin Dependent article > >




[h=3]What's a Normal Hemoglobin A1c Test?[/h] For people without diabetes, the normal range for the hemoglobin A1c test is between 4% and 5.6%. Hemoglobin A1c levels between 5.7% and 6.4% indicate increased risk of diabetes, and levels of 6.5% or higher indicate diabetes. Because studies have repeatedly shown that out-of-control diabetes results in complications from the disease, the goal for people with diabetes is a hemoglobin A1c less than 7%. The higher the hemoglobin A1c, the higher the risks of developing complications related to diabetes.
People with diabetes should have this test every three months to determine whether their blood sugars have reached the target level of control. Those who have their diabetes under good control may be able to wait longer between the blood tests, but experts recommend checking at least 2 times a year.
Patients with diseases affecting hemoglobin such as anemia may get abnormal results with this test. Other abnormalities that can affect the results of the hemoglobin A1c include supplements such as vitamins C and E and high cholesterol levels. Kidney disease and liver disease may also affect the result of the hemoglobin A1c test.
http://diabetes.webmd.com/guide/glycated-hemoglobin-test-hba1c
 

Imranpak

Chief Minister (5k+ posts)
Informative article but many medical reports will disagree with it. Medicine often contains elemants that make a patient feel worse so should be avoided after all we don't know the ingrediants they contain.

The media, controlled by the government often plays on people's fears encouraging them to take medicine or injections that are bad for them. I have often observed that people taking medicine or undergoing mainstream forms of hospital treatment complaint of feeling even worse then before. When it comes to health one should always do their own research instead of taking the advise of so-called doctors who have their own agenda's.
http://www.naturalnews.com/diabetes.html
http://www.naturalnews.com/030150_diabetes_Americans.html
http://www.realdiabetestruth.com/how-the-latest-dietary-research-can-benefit-diabetics/
 

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