Criticise Imran Khan over his lack of experience in governance.
When Imran Khan give examples of Shaukat Khanum Hospital and Nimal University, attack these institutions. Don't worry if these institutions serving the people of Pakistan suffer in the process.
When Imran Khan agitates against the defamation campaigns against these institutions, ask him to stop referring to the good work he's done at these institutions and admit that he lacks experience as compared to the likes of Sharifs and Zardaris.
Imran Khan will bow down and succumb to the pressure.
The political rivals, especially Noora League will be successful in establishing that Imran Khan doesn't have what it takes to run a country.
Fact (forgotten in the above tactics and assumptions)
As per historical records Imran Khan has never given up and bowed down regardless of the situation. Hence, it's unlikely that he'll give up this time.